Semble Integration With SignatureRx
With the Semble integration, you can submit patient prescriptions directly to SignatureRx from within Semble.
Make sure your Semble role includes editing permissions for Lab and pharmacy settings before you begin.
This article covers:
- Setting up SignatureRx in Semble
- Submitting a prescription to SignatureRx
Set Up SignatureRx in Semble
Follow these steps once you have the required permissions:
1. Open Lab and Pharmacy Settings
Go to Settings in Semble and select the Lab and pharmacy settings tab.
2. Add a Pharmacy Account
Scroll to the Pharmacy settings section and click Add pharmacy account.
3. Enter Your Integration Details
Fill in the required fields:
- Provider: Select SignatureRx
- Name: Enter your practice name or the clinician name registered with SignatureRx
- Source: Enter your SignatureRx Clinic ID and six digit PIN in this format:
CLINICID.SIXDIGITPIN

4. Save Your Settings
Click Save to confirm.
Your integration is now active and ready to use.
Submit a Prescription to SignatureRx
Once SignatureRx is connected, you can submit prescriptions at any time.
1. Create the Prescription
Create a patient prescription as usual.
2. Open the Pharmacy Integration
Click the pharmacy integration icon.
3. Select SignatureRx
Choose SignatureRx from the dropdown menu.
You may enter any notes or comments for the prescription.
5. Send the Prescription
Click Send. The prescription is then submitted to SignatureRx and a patient's email is sent automatically with their prescription details.
Additional Steps You May Need To Complete
You might need to take extra actions within SignatureRx if:
- The system requires you to release the prescription
- The prescription was sent on your behalf
- The prescription was signed by a clinician without a SignatureRx prescriber account
If the Prescription Fails to Send
If something goes wrong, an error message will appear:
- As a pop-up on the prescriptions page
- On the prescription listing page
- On the individual prescription page
The error message will explain the reason for the failure.
You can also view all submission attempts and errors in the Logs tab of the patient record.

Costs and Charges
There are no additional costs from SignatureRx for this integration.
Please check directly with Semble regarding any fees they may apply.