SignatureRx is an advanced electronic private prescription system that enables clinicians and telemedicine providers to issue paperless, secure, and fully compliant prescriptions to pharmacies across the UK. This guide explains how SignatureRx works from a pharmacy perspective and how to access and dispense prescriptions.
1. SignatureRx allows prescriptions to be:
Patients do not present a paper prescription—instead, they provide:
2. Accessing a Prescription
To retrieve a prescription:
If the details match, the prescription will appear on screen.

3. Before Dispensing
Check the prescription status:
Available for dispensing → Safe to proceed
Do NOT dispense if status is:

4. Dispensing the Prescription
Only mark as dispensed once the medication is ready for collection or delivery.

After Dispensing
Key Benefits for Pharmacies
How SignatureRx Works for Pharmacies
Overview
This article explains how SignatureRx works from a pharmacy's perspective, including how to access, verify, and dispense a prescription.
Who does this apply to?
Pharmacy staff dispensing SignatureRx prescriptions. (Note: this article was found listed under the Patient section, but its content is written for pharmacy staff rather than patients.)
Key points
1. How does a pharmacy access a prescription?
Answer: Via signaturerx.co.uk, using the Prescription ID and patient date of birth.
Go to signaturerx.co.uk, click "Dispense Prescription", enter the Prescription ID and patient date of birth, select the Pharmacy Group, and click Search. If the details match, the prescription appears on screen.
2. What should be checked before dispensing?
Answer: The prescription status must show it's available for dispensing.
Proceed only if the status shows "Available for dispensing." Do not dispense if the status is Voided, Expired, or Already dispensed.
3. How is a prescription marked as dispensed?
Answer: By downloading, reviewing, preparing the medication, and clicking "Mark As Dispensed".
Download and review the prescription, prepare the medication, complete all required fields, and click "Mark As Dispensed" only once the medication is ready for collection or delivery. After this, the prescription is complete, cannot be dispensed again elsewhere, and a secure audit trail is created.
Source link:
https://help.signaturerx.co.uk/portal/en/kb/articles/how-signaturerx-works-for-pharmacies